Evidence-based longevity

Live longer.
Skip the noise.

We read the studies, grade every claim, and hand you the signal — so you know what actually works and what's just hype.

Every claim graded: 🥇 Gold 🥈 Silver 🥉 Bronze ⚠️ Emerging
Why you can trust us

Every claim is graded and cited.

We read the studies, check the methodology, and flag conflicts of interest — so you always know exactly how solid the ground is before you act on anything.

🥇 Gold

Meta-analysis, systematic review, or large replicated trial.

🥈 Silver

A solid randomized trial or strong observational data.

🥉 Bronze

Preclinical or small pilot — promising, not proven.

⚠️ Emerging

Early signal — interesting, but treat with caution.

The weekly signal

This Week in Longevity

🥇

Aging clocks do respond to anti-aging treatments — now we know which to trust.

A Nature Medicine study harmonized 51 intervention trials and showed 16 epigenetic clocks plus 94 biomarkers actually move with diet, drugs, and lifestyle.

PMID 42629466
🥇

Robotic knee surgery: no better than conventional — just pricier.

A masked Lancet trial of 339 patients found the Mako robotic-arm system delivered no measurable benefit over standard knee replacement.

PMID 42624811
🥈

How obesity raises cancer risk: stressed fat cells turn into "zombie cells."

A review connects excess fat to premature cellular senescence and the inflammatory SASP that creates a tumor-friendly environment.

PMID 42631902
🥈

Keto and biological age: not one-size-fits-all.

In 58 adults on a 12-week ketogenic diet, the "pace of aging" clock split people into responders and non-responders — and responders felt dramatically better.

PMID 42632233
🥈

The hidden muscle cost of Ozempic-style weight-loss drugs.

A review warns GLP-1 drugs can shrink protein intake enough to trigger "secondary sarcopenia" in older adults — protect your protein and keep lifting.

PMID 42631799

Read this week's full digest →

Get the signal.
Not the noise.

One curated digest a week. The studies worth acting on, graded and explained in plain English. Free, forever.